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Beyond PRP: Restore-IT

beyond-prp“Amniotic Fluid Cells in Pure Protein Rich Plasma with a Natural Extra Cellular Matrix”
Greco Medical Group utilizes a proprietary method that activates FDA regulated amniotic cells (Restore Amnion), rich in regenerative proteins and growth factors, with a natural extra cellular matrix and a “purified form of PRP” to form a regenerative complex that goes beyond platelet rich plasma formulas.

How is Restore-IT different than PRP?

  • The added Amniotic Fluid cells, by New Life Medical

provide “higher levels of growth factors”

  • Concentrating plasma proteins and other adhesion molecules, form an “Extra Cellular Matrix” ECM that entraps the growth factors in a natural matrix graft to recruit regenerative cells that reduce pain and regenerates tendons, ligaments, skin, bone and hair.
  • Our process has the “I-RA” – Interluken Antagonist that “reduces pain”
  • Our Process has the “A2M” – a protein that modifies Osteoarthritis
  • Restore-IT Regenerative Complex

What is the advantage of AF over Adipose (Fat) Derived Stem Cell and Bone Marrow Aspirate?

  • It does not require liposuction to harvest fat to use as a scaffold or matrix
  • It does not require painful aspirating or Bone marrow from the pelvis
  • Only FDA approved study centers are allowed to use Adipose Stem cells
  • AF is FDA approved
  • It is less expensive

Where do the Amniotic Fluid Cells come from?

Amniotic fluid is a liquid that protects the fetus and provides a supportive environment for fetal growth, is encapsulated within the amniotic membrane. The University of Miami Tissue Bank recovers amniotic fluid with consent from healthy mothers surgically during cesarean section births. All fluids are serologically tested within 30 days of the scheduled surgery to the strictest FDA standards and AATB guidelines. Once serology reports and donor charts are reviewed and released by a medical director or designee, the fluid is then aseptically processed in a controlled environment via a gentle filtration and centrifugation cycle to remove tissue debris.

What is in Amniotic Fluid Cells?

AF contains various proteins that support cell proliferation, movement and differentiation. AF also

includes collagen substrates, growth factors, amino acids, polyamines, lipids, carbohydrates, cytokines, extracellular matrix molecules like hyaluronic acid and fibronectin cells and other chemical compounds that are needed for tissue protection and repair.

What can Amniotic Fluid Cells do?

These components of AF have been shown to activate the body’s own healing response, which is characterized by minimal inflammatory activity and regenerative rather than scar-mediated healing.

AF is a protein-rich fluid with proven regenerative potential. Its components regulate and maintain regenerative tissue processes. This fluid has a complex array of inherent growth factors and cytokines that provide protection to the fetus during pregnancy. Because of its inherent anti-inflammatory and anti-scarring properties,

AF has been successfully used clinically as an additive for surgical applications

associated with soft tissue procedures. To ensure that these inherent properties

are maintained during processing and preparation for clinical implantation, testing must be performed.

How does this process work?

Our method involves drawing your blood and in a proprietary four step process then (1) separate, (2) concentrate, (3) mix growth factors and cytokines with a natural extra cellular matrix and the (4) amniotic cells. This complex then undergoes a unique activation process to release certain pain reducing (proteins) and regenerative cells.

Why is Restore Amniotic Fluid Cells advantageous over other AF products?

1- NO DMSO is utilized. DMSO is a very toxic cryoprotectant and utilizing DMSO harms the amount of growth factors, cytokines, collagen, amino acids, polymines, carbohydrates, ECM molecules like hyaluronic acid and fibronectin.

2-The absence of DMSO allows for the maximum amount of growth factor and cytokines to be delivered because there is no dilution to the fluid.

What can Restore-IT be used for?

  • Pain Reduction
  • Tendons, Ligaments, Joints
  • Wounds
  • Skin Rejuvenation
  • Surgical and Non-surgical hair improvement



Dear Dr. Greco,

I’m compelled to write you a note to tell you how pleased I am with the results of your amazing technology. It’s just been a little over a month since receiving your CRP shot–I hope I called it by its correct name. Before I came, as you know, I could barely walk because my left knee was in such bad shape. I had a hard time standing, I could only go up stairs with use of a handrail by using my arm strength to lift me up. A local doctor told me that I was going to need knee replacement surgery. It’s November 6 now about 6 weeks since your help and today I went to a local park and walked 4 miles and then later went to the Y and shot some baskets (I didn’t play just shot around). Tonight there is absolutely no pain or discomfort, no swelling, no tightening. Amazingly enough there is actually a spring in my step these days. I thought I would never get to do the things I did today ever again and I am extremely grateful that you have researched and developed this technology. I was telling my son today that what has happened to me is nothing short of a miracle. This is why I had to write–thank you!

Brad, (Virginia)